Peptide glossary
Nitric oxide (NO) system
A signalling gas that relaxes blood vessels and modulates inflammation; several BPC-157 findings run through it.
Nitric oxide is a short-lived gas produced by nitric oxide synthase enzymes in blood vessel walls, nerves and immune cells. In vessels it causes the smooth muscle to relax, lowering local resistance and increasing flow. It also modulates inflammation, platelet activity and nerve signalling, and its overproduction or underproduction is implicated in a wide range of pathology.
The NO system appears in the profiles chiefly through BPC-157. The laboratory that discovered the peptide has published extensively on its interaction with nitric oxide, reporting that it counters both inhibition of NO synthesis and NO excess in animal models, an effect they describe as stabilising vascular tone. It is one of the two mechanistic threads, alongside angiogenesis, that the literature offers for the compound's healing findings, and it is the reason the profile's safety section notes a theoretical effect on blood pressure.
As with the rest of the BPC-157 literature, the NO findings come mainly from one group and from animals. The profile states this plainly.
Compounds where this term matters
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Research & educational use only. Definitions are informational and not medical advice. Products are supplied for laboratory research and are not for human use.