How to administer a subq peptide injection — site selection, needle choice, technique, and rotation.
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The vast majority of peptide protocols use subcutaneous (subq) injection — into the fatty tissue just below the skin, not the muscle below it. Once you've done a handful, it's effectively painless and takes under thirty seconds.
Four common subq sites:
Abdomen and outer thigh are the workhorses. Rotate across sites so no single point receives repeated injections within 5–7 days.
A small bead of blood at the withdrawal point is normal; it means you nicked a superficial capillary. Apply pressure until it stops. Bruising at subq sites is common and doesn't indicate error — you're injecting into a vascular area.
If blood appears in the syringe as you aspirate before pushing the plunger, withdraw the needle, discard the syringe, and start over at a new site. This is uncommon with subq technique but worth catching.