The 20 mg vial: the bridge
The 20 mg vial exists for the middle of a protocol — past the low-amount titration phase the 10 mg vial serves, but not yet at the point where a 30 mg reservoir empties before it expires. At 10 mg/mL reconstituted, it halves the syringe volume of the 10 mg vial for the same amount, which is the practical reason to move up.
For the compound itself — receptor pharmacology, research background, comparisons — see the retatrutide hub.
What's in this vial
| Spec | Detail |
|---|
| Contents | 20 mg retatrutide, lyophilised (freeze-dried) powder |
| Form | Sealed single vial, sterile stoppered |
| Purity | ≥98% by HPLC |
| Receptors | GLP-1 / GIP / glucagon (triple agonist) |
| Ships | Canada-wide, priced in CAD |
| Not included | Bacteriostatic water, syringes — ordered separately |
Reconstituting a 20 mg vial
Adding 2 mL of bacteriostatic water gives:
20 mg ÷ 2 mL = 10 mg/mL
| Amount | Volume | U-100 syringe |
|---|
| 2 mg | 0.20 mL | 20 units |
| 4 mg | 0.40 mL | 40 units |
| 6 mg | 0.60 mL | 60 units |
| 8 mg | 0.80 mL | 80 units |
10 mg/mL is arguably the most convenient concentration in the range: every whole-milligram amount lands on a round 10-unit mark, and even amounts are trivial to read off. Confirm your own figures with the dosage calculator.
The trade-off against the 10 mg vial is resolution. At 10 mg/mL a single syringe unit is 0.1 mg, versus 0.05 mg at 5 mg/mL — so small adjustments are coarser here. That is rarely the binding constraint mid-protocol, but it is the reason the smaller vial suits early titration.
How many doses is a 20 mg vial?
At 2 mL of bacteriostatic water, a 20 mg vial gives:
- 10 aliquots at 2 mg
- 5 aliquots at 4 mg
- ~3 aliquots at 6 mg
At a weekly cadence the higher amounts are the sweet spot: 5 aliquots at 4 mg is a little over a month, which is roughly the ~30-day refrigerated shelf life of the reconstituted solution. At 2 mg weekly this vial will expire with half its contents unused — that is the 10 mg vial's job.
Storage and handling
Refrigerate the lyophilised vial at 2–8 °C. Once reconstituted, refrigerate and use within about 30 days. Bacteriostatic water (0.9% benzyl alcohol) permits multiple draws; sterile water is single-use. Don't freeze reconstituted solution, keep it out of light, and discard anything cloudy or containing particulate. See the storage guide and reconstitution walkthrough.
Regulatory status: investigational everywhere
Retatrutide is an investigational compound with no marketing approval from Health Canada, the FDA, or any other regulator anywhere. It remains in clinical development, has never been authorised for human use, and there is no approved version of it and no prescription route to it. This vial is supplied for laboratory research use only and ships within Canada only.
Retatrutide and anti-doping
WADA's S0 (non-approved substances) category covers any pharmacological substance with no current approval from any governmental health authority for human therapeutic use, explicitly including drugs under clinical development. Retatrutide has no such approval.
By that definition it falls inside S0, which is prohibited at all times, in and out of competition. Tested athletes should treat retatrutide as off-limits and confirm against the WADA Prohibited List directly.
Frequently asked questions
How many doses are in a 20 mg retatrutide vial?
Reconstituted with 2 mL of bacteriostatic water, a 20 mg vial gives about 10 aliquots at 2 mg, 5 at 4 mg, or 3 at 6 mg. Because the reconstituted solution keeps roughly 30 days, the vial is best matched to a weekly cadence at the higher amounts.
How do you reconstitute a 20 mg retatrutide vial?
Add bacteriostatic water slowly down the vial wall and let the cake dissolve without shaking. With 2 mL, a 20 mg vial gives 10 mg/mL — so 2 mg is 0.2 mL, or 20 units on a U-100 insulin syringe, and every whole milligram lands on a round 10-unit mark.
Should I buy the 10 mg or the 20 mg retatrutide vial?
The 10 mg vial gives finer resolution (0.05 mg per syringe unit) and suits early titration at low amounts. The 20 mg vial is more economical per milligram and gives rounder volumes at higher amounts, but at 2 mg weekly it will reach its 30-day reconstituted shelf life with half the vial unused.
Is retatrutide approved anywhere?
No. Retatrutide is investigational and holds no marketing approval from Health Canada, the FDA, or any other regulator. It remains in clinical development and is supplied here for laboratory research use only.
Is retatrutide banned in sport?
Yes, in effect. WADA's S0 category covers substances with no approval from any health authority for human use, including drugs in clinical development — which describes retatrutide. S0 substances are prohibited at all times, in and out of competition.
Do you ship retatrutide across Canada?
Yes — Canada-wide, priced in CAD, with a flat $25 shipping rate. We do not ship to the United States or internationally.
