GLP-1 · GIP · Glucagon
Retatrutide in Canada
Retatrutide is a triple-agonist research peptide that targets three metabolic receptors — GIP, GLP-1, and glucagon — on a single backbone. Canada Peptides carries research-grade retatrutide in four formats, priced and shipped in CAD. Everything below is for research and educational use only.
Retatrutide — for sale
What is retatrutide?
Retatrutide is the first triple agonist to reach Phase 3 development. It engages the GIP and GLP-1 receptors — the axis behind the current generation of metabolic-research compounds — and adds glucagon-receptor activation, the mechanistic bet that distinguishes it from dual agonists. For the full mechanism, see the retatrutide research overview.
Formats: vials and the reloadable pen
Retatrutide is offered as draw-up vials in 10 mg, 20 mg, and 30 mg, plus a 15 mg reloadable pen for dial-a-dose delivery without vial draw-up. The pen guide covers how to load, prime, and dial it.
Dosing in research
Published Phase 2/3 protocols point to once-weekly subcutaneous administration with gradual titration. Our dosing-math and reconstitution guides cover the handling math. This is research context only — not a dosing recommendation for human use.
Retatrutide vs Ozempic and Tirzepatide
By receptor coverage: semaglutide (Ozempic) is a single GLP-1 agonist, tirzepatide is a dual GLP-1/GIP agonist, and retatrutide is a triple GLP-1/GIP/glucagon agonist. The GLP-1 receptor agonists comparison breaks down how the three differ mechanistically.
Further reading
Retatrutide Side Effects: What the Research Reports
What published retatrutide trials report about tolerability and the side-effect profile of the triple agonist. Investigational compound — research use only, not medical advice.
Retatrutide vs Ozempic (Semaglutide): How They Differ
Retatrutide vs Ozempic — a triple agonist versus a single GLP-1 agonist. Receptor coverage, mechanism, and what the trial data covers. Research use only.
Retatrutide Dosing: A Research Reference
How retatrutide was dosed in published Phase 2/3 research — titration schedule, frequency, and the reconstitution math behind it. Research use only, not medical advice.
Retatrutide Pen: How to Use It and Where to Buy in Canada
Retatrutide pen for sale in Canada — what the 15 mg reloadable 3 mL pen is, how to load, prime, and dose it, how it compares to vials, and where to buy it. Research use only.
GLP-1 receptor agonists compared
Semaglutide vs Tirzepatide vs Retatrutide—mechanism, half-life, dosing, and the evidence gap.
Retatrutide — a research overview
Triple GIP/GLP-1/glucagon receptor agonist in phase 3 development with emerging data on metabolic effects beyond appetite suppression.
Retatrutide FAQ
- Is retatrutide for sale in Canada?
- Yes. Research-grade retatrutide is available in Canada from Canada Peptides in four formats — 10 mg, 15 mg (reloadable pen), 20 mg, and 30 mg — priced and shipped in CAD. It is supplied strictly for laboratory and research use.
- Where can I buy retatrutide in Canada?
- You can order research-grade retatrutide directly on this page. All four formats ship within Canada in CAD, for research use only.
- What does retatrutide do?
- Retatrutide is a synthetic triple agonist: it activates the GIP, GLP-1, and glucagon receptors on a single peptide backbone. The addition of glucagon-receptor activation is the mechanistic feature that distinguishes it from single- and dual-agonist compounds.
- How is retatrutide dosed in research?
- Published Phase 2 and Phase 3 protocols use once-weekly subcutaneous administration with gradual titration. See our dosing-math and reconstitution guides for handling context. Nothing here is medical advice or a dosing recommendation for human use.
- Retatrutide vs Ozempic (semaglutide) — what's the difference?
- By receptor coverage: semaglutide (the compound in Ozempic) is a single GLP-1 agonist, tirzepatide is a dual GLP-1/GIP agonist, and retatrutide is a triple GLP-1/GIP/glucagon agonist. We compare the three in the GLP-1 receptor agonists overview.
- Is retatrutide research use only?
- Yes. Every retatrutide SKU is supplied strictly for laboratory and research use until accompanied by an applicable prescription. It is an investigational compound; its profile in humans is still being characterized in clinical trials. Nothing here is medical advice.
Research & educational use only. This page is informational and does not constitute medical advice or a therapeutic claim.