Mitochondrial & metabolic signalling
This category covers compounds studied around mitochondrial function and substrate metabolism rather than a hormonal axis. It is deliberately small: two compounds with genuinely distinct mechanisms, both active areas of research into cellular energy handling. Priced and shipped in CAD, for laboratory and research use only.
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA rather than the nuclear genome — one of a small set of mitochondrial-derived peptides identified in the last two decades. Research interest centres on AMPK signalling and metabolic regulation. Because it sits at the intersection of energy and ageing research, it is often compared against longevity compounds — see Epithalon vs MOTS-c.
Worth stating plainly: SLU-PP-332 is a small-molecule oestrogen-related receptor (ERR) agonist, not a peptide. It sits in this category because the research context — mitochondrial biogenesis and exercise-mimetic signalling — is the same. It handles differently from a lyophilized peptide, so read the compound page before planning storage.
Energy and metabolic research overlap heavily, and the boundary here is mechanism: incretin and GHRH compounds sit under metabolic, while this category is limited to compounds acting on mitochondrial and receptor-level energy signalling. NAD+ sits under longevity for the same reason.
MOTS-c dosage — research dosing notes
What the literature actually reports on MOTS-c dosage: the rodent mg/kg ranges from Lee 2015 and Reynolds 2021, the human trial regimens, half-life context, and reconstitution math for a 10 mg vial.
SLU-PP-332 — a research overview
A measured research overview of SLU-PP-332: how this pan-ERR agonist works as an exercise mimetic, what the rodent data actually shows, its pharmacokinetic limits, and why there is still no human evidence.
MOTS-c — a research overview
Mitochondrial-derived peptide regulating AMPK and metabolic aging, with emerging human data on insulin sensitivity and exercise physiology.
Research & educational use only. This page is informational and does not constitute medical advice or a therapeutic claim.