Resources/Journal
Journal
Research write-ups, new compound deep dives, and updates from the NeuroForge team.
blog
6 min
Ipamorelin vs CJC-1295 — compared
Ipamorelin vs CJC-1295: two different receptors, two different half-lives, two different depths of human data. A research comparison of the ghrelin-receptor agonist and the long-acting GHRH analog.
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6 min
GHRP-2 vs GHRP-6 — compared
GHRP-2 vs GHRP-6 compared across sequence, receptor pharmacology, half-life, GH response and appetite — including where the common claim that GHRP-2 avoids hunger breaks down against the published data.
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5 min
Semax dosage — research dosing notes
What the literature actually reports on Semax dosage: the 0.1% and 1% intranasal concentrations, the 6,000 µg/day post-stroke regimen, half-life context, and reconstitution math for a 5 mg vial.
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5 min
MOTS-c dosage — research dosing notes
What the literature actually reports on MOTS-c dosage: the rodent mg/kg ranges from Lee 2015 and Reynolds 2021, the human trial regimens, half-life context, and reconstitution math for a 10 mg vial.
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6 min
GHK-Cu dosage — research dosing notes
A research overview of GHK-Cu dosage: the 0.1–2% topical concentrations used in published trials, the preclinical injected figures, the short circulating half-life, and reconstitution math for lyophilized vials. Literature summary only, not medical advice.
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5 min
CJC-1295 dosage — research dosing notes
A literature review of CJC-1295 dosage: the weight-scaled weekly doses used in the published human trials of the DAC form, the half-life data behind that cadence, and reconstitution math for a 10 mg research vial.
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6 min
Tesamorelin dosage — research dosing notes
A research reference on tesamorelin dosage: the fixed 2 mg daily dose used across the phase 3 trials, why the three approved formulations list different milligram figures, the sub-hour half-life, and the reconstitution math. A literature overview, not medical advice.
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6 min
BPC-157 dosage — research dosing notes
A literature review of BPC-157 dosage: the animal dose ranges actually studied, the measured pharmacokinetics in rats and dogs, and why no human dose has been established. Research use only.
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6 min
Tirzepatide dosage — research dosing notes
A literature overview of tirzepatide dosage: the 2.5 mg initiation step, four-week titration cadence, and 5/10/15 mg maintenance levels used in the trials, the ~5-day half-life behind once-weekly dosing, and reconstitution math for lyophilized vials. Research context only, not medical advice.
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5 min
Semaglutide dosage — research dosing notes
A research-literature overview of semaglutide dosage: the STEP and SUSTAIN escalation schedules, the 7-day half-life behind the four-week cadence, and the reconstitution math from lyophilized vial to syringe units.
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5 min
Retatrutide dosage — research dosing notes
A research-framed overview of retatrutide dosage: the titration schedules and doses used in clinical trials, its ~6-day half-life, and reconstitution math. Research-use-only, not medical advice.
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5 min
Ipamorelin dosage — research dosing notes
A research overview of ipamorelin dosage: the reconstitution math, the intravenous doses and twice-daily cadence reported in the literature, and the ~2-hour half-life context — framed strictly as a laboratory-research reference, not medical advice.
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5 min
SLU-PP-332 — a research overview
A measured research overview of SLU-PP-332: how this pan-ERR agonist works as an exercise mimetic, what the rodent data actually shows, its pharmacokinetic limits, and why there is still no human evidence.
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6 min
TB-500 dosage — research dosing notes
A literature review of TB-500 dosage: what the published thymosin beta-4 trials actually dosed, the intravenous pharmacokinetics on record, and why no human dose has been established for the TB-500 fragment itself.
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6 min
HCG — a research overview
A measured research overview of the HCG peptide: its glycoprotein structure, LHCGR mechanism and cAMP signalling bias, the hypogonadotropic hypogonadism and ovulation-trigger data, and why the approved label rejects the obesity claim.
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5 min
Tesofensine — a research overview
A measured research overview of tesofensine: the triple monoamine reuptake inhibitor's mechanism, the TIPO-1 trial data, how it compares to GLP-1 peptides, and honest limits of the evidence.
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5 min
GHRP-6 — a research overview
A measured research overview of the GHRP-6 peptide: its ghrelin-receptor mechanism, growth-hormone and appetite effects, CD36 cytoprotective research, and how it compares to GHRP-2 and ipamorelin.
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5 min
GHRP-2 — a research overview
A measured research overview of the GHRP-2 peptide (pralmorelin): its ghrelin-receptor mechanism, the growth hormone, cortisol, and appetite data, and how it compares to GHRP-6 and ipamorelin.
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5 min
Melanotan 2 — a research overview
A measured research overview of melanotan 2: its melanocortin-receptor mechanism, how it compares to afamelanotide and PT-141, and the honest limits of the human data.
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5 min
DSIP — a research overview
A measured research overview of DSIP (delta sleep-inducing peptide): its structure, proposed mechanism, the mixed sleep and stress-axis data, and where the DSIP peptide sits versus related compounds.
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4 min
Generic Semaglutide in Canada: What Health Canada's 2026 Approvals Mean
Canada is the first G7 country to approve generic semaglutide. What Health Canada approved in 2026, why the patent lapsed, pricing and availability — and how prescription generics differ from research-grade semaglutide.
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4 min
KPV — a research overview
A measured research overview of the KPV peptide: what the lysine-proline-valine tripeptide is, its PepT1/NF-kB anti-inflammatory mechanism, the preclinical colitis and skin data, and honest limits.
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5 min
Kisspeptin — a research overview
A measured research overview of the kisspeptin peptide: its role upstream of GnRH in the HPG axis, the kisspeptin-10 vs kisspeptin-54 human trial data, and honest caveats on data maturity.
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5 min
Glutathione — a research overview
A measured research overview of the glutathione injection: its antioxidant biochemistry, the intravenous bioavailability rationale, and what Parkinson's and skin-lightening trials actually show.
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1 min
BPC-157 Dosing: A Research Reference
How BPC-157 is handled in research — administration route, reconstitution, and the dosing math. Research use only, not medical advice.
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1 min
BPC-157 Side Effects: What the Research Reports
What the literature reports about BPC-157 tolerability, framed for research. Research use only, not medical advice.
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1 min
BPC-157 Oral vs Injectable: What the Research Uses
Oral vs injectable BPC-157 — the routes seen in research and the stability considerations behind them. Research use only, not medical advice.
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1 min
Tirzepatide Side Effects: What the Research Reports
What the published literature reports about tirzepatide's tolerability and side-effect profile, framed for research. Research use only, not medical advice.
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1 min
Tirzepatide Dosing: A Research Reference
How tirzepatide is dosed in published research — once-weekly administration, titration, and reconstitution math. Research use only, not medical advice.
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1 min
Is Tirzepatide the Same as Mounjaro? Tirzepatide vs Mounjaro & Zepbound
Tirzepatide vs Mounjaro — the difference between a compound and its brand names. Mounjaro and Zepbound are tirzepatide; what research-grade tirzepatide is and isn't. Research use only.
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1 min
Semaglutide Side Effects: What the Research Reports
What the published literature reports about semaglutide's tolerability and side-effect profile, framed for research. Research use only, not medical advice.
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1 min
Semaglutide Dosing: A Research Reference
How semaglutide is dosed in published research — once-weekly administration, titration, and reconstitution math. Research use only, not medical advice.
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2 min
Is Semaglutide the Same as Ozempic? Semaglutide vs Ozempic
Semaglutide vs Ozempic — the difference between a compound and its brand names. Ozempic and Wegovy are semaglutide; what research-grade semaglutide is and isn't. Research use only.
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2 min
Retatrutide Side Effects: What the Research Reports
What published retatrutide trials report about tolerability and the side-effect profile of the triple agonist. Investigational compound — research use only, not medical advice.
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2 min
Retatrutide vs Ozempic (Semaglutide): How They Differ
Retatrutide vs Ozempic — a triple agonist versus a single GLP-1 agonist. Receptor coverage, mechanism, and what the trial data covers. Research use only.
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2 min
Retatrutide Dosing: A Research Reference
How retatrutide was dosed in published Phase 2/3 research — titration schedule, frequency, and the reconstitution math behind it. Research use only, not medical advice.
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4 min
Retatrutide Pen: How to Use It and Where to Buy in Canada
Retatrutide pen for sale in Canada — what the 15 mg reloadable 3 mL pen is, how to load, prime, and dose it, how it compares to vials, and where to buy it. Research use only.
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7 min
NAD+ — a research overview
NAD+ is the cell's central redox coenzyme and the substrate sirtuins and PARPs consume. A research overview of its mechanism, the bioavailability problem, precursor strategies, and what the human data actually shows.
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3 min
Semax — a research overview
Semax is a synthetic ACTH(4-10) analogue studied as a nootropic and neuroprotective peptide. Its mechanism, the BDNF/NGF neurotrophic story, and what the (Russia-dominated) research actually shows.
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4 min
Semaglutide — a research overview
Mechanism, half-life, dose-response curve, and the human literature behind the most-studied GLP-1 receptor agonist of the last decade.
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5 min
GLP-1 receptor agonists compared
Semaglutide vs Tirzepatide vs Retatrutide—mechanism, half-life, dosing, and the evidence gap.
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5 min
Tesamorelin — a research overview
Stabilized GHRH analogue with FDA approval for HIV lipodystrophy, selective visceral fat reduction, and pulse-amplification mechanism.
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6 min
BPC-157 vs TB-500—healing peptides compared
Two foundational soft-tissue research peptides, their distinct mechanisms, and why they're often stacked together.
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3 min
The four-phase research cycle
How to run a peptide protocol like an engineer — define the endpoint, measure the baseline, run the cycle, review the data.
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6 min
Storing peptides — the cold chain from shipping to vial
Lyophilized and reconstituted stability windows, temperature ranges, and practical storage logistics.
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7 min
Growth-hormone secretagogues—the category guide
GHRH analogues and GHRPs explained—mechanisms, selectivity, and why they're often combined.
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4 min
Tirzepatide — a research overview
Dual GIP/GLP-1 receptor agonist with extended half-life, dose-response curve, and the SURPASS and SURMOUNT trial literature.
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6 min
CJC-1295—with DAC or without?
Half-life, pulsatile vs continuous GH release, and why we carry both versions.
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6 min
Reading a peptide Certificate of Analysis — what to check
Anatomy of a COA, red flags, and how to verify identity and purity.
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6 min
Sleep & Longevity Peptides: DSIP, Epithalon, MOTS-c
DSIP, Epithalon, MOTS-c—three axes of biological aging and why they're discussed together.
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5 min
Retatrutide — a research overview
Triple GIP/GLP-1/glucagon receptor agonist in phase 3 development with emerging data on metabolic effects beyond appetite suppression.
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5 min
Thymosin Alpha-1 — a research overview
28-aa thymic peptide driving T-cell and NK-cell immunity, with established clinical use in hepatitis and emerging COVID-era research.
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6 min
What research-grade peptides mean — regulatory definitions and quality
RUO labeling, cGMP, purity specs, and the practical gap between grades.
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7 min
Skin Peptides Explained: Melanotan 2, GHK-Cu & KPV
Melanotan 2, GHK-Cu, KPV, and the blends—structural, pigmentation, and dermal research.
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5 min
Selank — a research overview
Synthetic anxiolytic heptapeptide with GABAergic and immunomodulatory roots, clinically approved in Russia for stress and anxiety.
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5 min
BPC-157 — a research overview
15-amino-acid peptide derived from gastric protein with pro-angiogenic and tissue-protective mechanisms across soft-tissue and neurological models.
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7 min
AOD-9604 vs HGH Fragment 176-191—the myth
They're the same peptide. The confusing names explained, the failed trials, and why we list both.
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5 min
Subcutaneous vs intramuscular injection — routes and pharmacokinetics
Absorption kinetics, needle sizing, injection sites, and when to choose each route.
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4 min
MOTS-c — a research overview
Mitochondrial-derived peptide regulating AMPK and metabolic aging, with emerging human data on insulin sensitivity and exercise physiology.
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5 min
TB-500 — a research overview
Synthetic Thymosin Beta-4 analog with G-actin binding activity, cell-migration effects, and a mixed pre-clinical/cross-species literature.
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4 min
Epithalon — a research overview
Synthetic pineal-mimicking tetrapeptide, telomerase activation claims, and why the Russian literature dominates the dataset.
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6 min
Peptide reconstitution basics — lyophilized to liquid
Diluent choice, volume math, syringe mechanics, and storage after reconstitution.
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5 min
Ipamorelin — a research overview
Selective GHRP/ghrelin agonist with GH-pulse amplification, minimal cortisol spillover, and common stacking protocols.
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5 min
GHK-Cu — a research overview
Copper-binding tripeptide mechanism, tissue distribution, and the dermal and systemic literature behind this naturally-occurring regulator.
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8 min
How peptides are made — synthesis 101
From amino acids to vial: solid-phase synthesis, coupling chemistry, cleavage, and purification.
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2 min
Why peptides, and why now
A brief landscape of where peptide research sits in 2026, why the GLP-1 wave unlocked adjacent categories, and what's next.
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3 min
How to read a peptide study
A compact framework for evaluating a peptide paper — what to check, what to discount, and how to tell mechanism from marketing.